Graduate Student Nishi Gondhiya in the Chemistry and Biochemistry Department here at Clarkson University will present about Design and development of wearable electrochemical sensor for dual detection and degradation of organophosphate pesticides in the environment:
Organophosphates (OP) are widely used as pesticides throughout the world due to their high efficiency in controlling pests, but inappropriate use of these compounds is detrimental to the environment and human health and can cause severe effects, including neurotoxicity, embryotoxicity, genotoxicity, cytotoxicity and immunotoxicity as well as long-term effects. Methyl-paraoxon (MP) is the most typical oxo-form of OP, which has attracted attention, not only because of its serious neurotoxicity and respiratory toxicity, but also for its common application as a nerve agent simulant to investigate structure properties of chemical warfare agents. Various analytical methods have been reported to date to detect MP, including chemiluminescence, high-performance liquid chromatography (HPLC) and colorimetry. Although these methods provide good accuracy and precision, the requisite instruments are expensive and impractical to carry around. This study presents a novel approach utilizing a flexible electrode doped with catalytic nanoparticles immobilized within a conductive polymer matrix for the electrochemical detection and degradation of MP. The modified electrode demonstrates efficient degradation of MP to para-nitrophenol (p-NP) owing to the catalytic activity of the nanoparticles. In addition, this platform enables one-step detection of MP, with sensitivity levels in the nM concentration range. The combined detection and degradation functions renders this platform a promising candidate for monitoring and controlling the presence of OPs in the environment.
Friday, October 25, 2024, 3:30 PM, BH Snell Hall 214Potsdam Campus
Zoom Information: Link
Meeting ID: 950 1099 7564
Passcode: chemistry